SNU researchers develop AI algorithm to facilitate novel therapy development
이 글자크기로 변경됩니다.
(예시) 가장 빠른 뉴스가 있고 다양한 정보, 쌍방향 소통이 숨쉬는 다음뉴스를 만나보세요. 다음뉴스는 국내외 주요이슈와 실시간 속보, 문화생활 및 다양한 분야의 뉴스를 입체적으로 전달하고 있습니다.
The university said on Wednesday the team led by its medical school professors Han Buhm and Jung Kee-hoon has developed an AI algorithm named Marco Polo that can efficiently discover marker genes, potential targets for medical intervention.
The research on the development was led by Kim Chan-woo, a Ph.D. student in computer engineering at the University of Washington, and Lee Han-bin, a SNU College of Medicine student, who contributed as co-first authors. Kim was affiliated with SNU¡¯s Dept. of Electrical and Computer Engineering during the research.
To understand pathogenesis-related proteins and their genes and develop a corresponding therapy, it is necessary to discover cell types and marker genes that can be therapeutic targets as well. For this discovery, researchers use single-cell RNA sequencing (scRNA-seq) technology, which makes it possible to classify specific cell groups such as rare cells by individually measuring each cell¡¯s gene expression and to discover key marker genes expressed in specific cell types.
However, this technology has an accuracy problem because human errors can occur in the preceding process of cell clustering.
The algorithm developers explained that artificial intelligence can replace manual classification by humans and help find important genes.
The researchers also said that they applied Marco Polo to human stem cell and liver data and successfully discovered marker genes that otherwise could not be properly classified with existing methodologies.
The research finding was published in a recent edition of Nucleic Acids Research.
[¨Ï Maeil Business Newspaper & mk.co.kr, All rights reserved]
Copyright © 매일경제 & mk.co.kr. 무단 전재, 재배포 및 AI학습 이용 금지
- Three contestants vie for stalking horse bidder for SsangYong Motor - Pulse by Maeil Business News Korea
- KT’s Q1 earnings at 11-year best, readying IPO of digital bank and e-book platforms - Pulse by Maeil Business News Korea
- S. Korea seeking to add futures option to carbon emission credit market - Pulse by Maeil Business News Korea
- SPC Group adds aesthetic touch to bakery and dining hangout - Pulse by Maeil Business News Korea
- Korean popular pub operator Yukjun goes under mid-tier private equity fund - Pulse by Maeil Business News Korea
- 강경준, 상간남 피소…사랑꾼 이미지 타격 [MK픽] - 스타투데이
- AI가 알아서 美 주식 투자…수익률 125% [천억클럽]
- “시스템 몰랐다”…이동윤, 250억 폰지 사기 혐의로 불구속 송치 - MK스포츠
- 이찬원, 이태원 참사에 "노래 못해요" 했다가 봉변 당했다 - 스타투데이
- 양희은·양희경 자매, 오늘(4일) 모친상 - 스타투데이